Dear colleagues,
Our team has a 2.5-year study engineer (IE) position (starting from January 2026 or soon after) to work on the ANR-funded RAVEN project (RNA metabolism in axonal biology and vesicle transport: insights from myotonic dystrophy type 1) in collaboration with teams from Centre of Research in Myology and ENS Paris-Saclay.
The successful candidate will help develop microfluidic models for neuron culture and conduct experiments aimed at characterizing axonal transport and synaptic connectivity in the context of myotonic dystrophy type 1, using live-cell imaging and microelectrode arrays and primary neurons from the DMSXL mice. The position is listed on https://pasteur-lille.fr/fondation/nous-rejoindre/ (only available in French). The English version of the job description is provided below.
Main responsabilities:
• Maintain the mouse colony and perform primary neuron cultures
• Develop and optimize microfluidic devices for different experimental models
• Conduct cellular neurobiology experiments, studying axonal transport using live-cell imaging and synaptic connectivity using MEA
• Ensure rigorous documentation, analysis, and reporting of experimental results
• Maintain a laboratory notebook, present results, and participate in writing scientific articles
Cross-functional responsibilities:
• Collaborate closely with other team members and collaborators to integrate results within a multidisciplinary framework
• Participate in project meetings, progress reports, and joint publications
• Contribute to data sharing, reproducibility, and harmonization of protocols among the consortium laboratories
• Support training activities (doctoral students, interns) on the laboratory’s experimental platforms
• Participate in common laboratory tasks in coordination with other technical staff to ensure its smooth operation
Technical skills
• Practical experience in the culture and maintenance of primary neurons
• Proficiency in live-cell imaging techniques and quantitative analysis (specific training will be provided)
• Experience with MEA technology and/or microfluidic cell culture devices (desirable, but not required)
• Ability to use and adapt fluorescent reporters and viral constructs for neuronal studies
• Proficiency in data analysis software (image analysis, electrophysiology tools, statistical software)
• Proficiency in English (B1 level) – our team is highly international and our working language is English (language training opportunities are available)
Soft skills:
• Strong attention to detail and adherence to experimental protocols
• Analytical mindset and ability to troubleshoot complex experiments
• Effective communication and collaboration skills in an interdisciplinary environment
• Adaptability and autonomy in managing experimental workflows
• Commitment to scientific rigor, reproducibility, and the quality of research results
Address for informal inquiries: devrim.kilinc@pasteur-lille.fr
To apply for this job please visit pasteur-lille.fr.