research engineer

The Institute of NeuroPhysiopathology (INP) in Marseille is recruiting:A research engineer to study subcellular relations

between APP and MT5-MMP in Alzheimer’s disease.

Beginning June 2021; duration 2 years; funded by the Vaincre Alzheimer Foundation

A two-year position as a research engineer is available from June 1, 2021 at the Institute of Neuro- physiopathology (INP, University of Aix-Marseille/CNRS) in the team of Dr. Santiago Rivera who studies the physiopathological mechanisms of Alzheimer’s disease. The project is developed in col- laboration with the NeuroCyto team of Dr Christophe Leterrier also at INP.

The candidate will be involved in a project aimed at elucidating the molecular and subcellular rela- tionships between the MT5-MMP protease and the amyloid precursor protein (APP) in neurons. For this, different approaches will be used, with protein expression by viral vectors in cultured neurons followed by live-cell, super-resolution and HCS microscopy as well as biochemical studies. Experi- ence in one or more of these techniques, especially microscopy, will be appreciated. In addition, experience in molecular biology or data analysis with bioinformatics tools could be useful.

The candidate should have a master’s degree or engineering degree in biomedical or biotechnological sciences, be enthusiastic and well-organized, have a taste for detail, a good analytical and learning capacity, be willing to work in a team and have good interpersonal and communication skills.

Applications must be written in French or English and contain: 1) A curriculum vitae. 2) A cover letter. 3) Two letters of reference.

Please send applications no later than March 10 to Dr. Santiago Rivera and Dr. Christophe Leterrier at the following e-mail addresses: /

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